Yes. Genetics is also a factor, but also a lifestyle choice. Low-nutrient diets weaken the body's ability to fight infections. Smokers and smokers stimulate gingival tissue more than non-smokers, and stress also affects their ability to fight the disease. Diseases that interfere with the body's immune system, such as leukemia and AIDS, may worsen the condition of the gums. In uncontrolled patients with diabetes, the body is more susceptible to infection and gum disease is more severe or difficult to control. Hormone levels are elevated in pregnant women, resulting in different responses of the gums to the bacteria found in the plaque and in many cases can result in a condition known as "gingivitis of pregnancy."